Lipofoods. Functional health food ingredients. Microencapsulation. Bioavailability

<h1>LIPOFOODS functional health food ingredients microencapsulation bioavailability</h1> <h2>microencapsulated iron</h2> LIPOFER tasteless iron high available iron bioavailable iron supplementation iron iron fortification ferric iron no oxidative iron iron metallic taste iron delivery system iron absorption iron milk/dairy products/supplements ingredients health food functional <h2>bioavailable calcium</h2> food ingredients microencapsulation LIPOCAL high availability calcium microencapsulated calcium calcium soy microencapsulation bioavailability <h2>phytosterol</h2> LIPOPHYTOL (plant) sterol (ester) o (esters) (plant) stanol (ester) o (esters) water dispersible phytosterols/sterols cholesterol management microencapsulated phytosterols/sterols plant sterols/phytosterols in milk, yogurts, dairy, spreads, soy, orange juic functional health food ingredients <h2>omega 3</h2> LIPOMEGA3 microencapsulated omega 3 omega 3 powder <h2>functional health</h2> <h2>millispheres</h2> MILLICAPSULAS millispheres millicapsulas milisphere milicapsule functional health food ingredients microencapsulation bioavailability Functional health ingredients for the food and beverage industry</h1> Lipofoods develops and manufactures functional health ingredients for the food and beverage industry. Lipofoods creates its nutritional and technological solutions combining the pharmaceutical knowledge and the expertise in microencapsulation of its mother company Lipotec. Lipofoods is located in an 8.000 m2 new facility equipped with cutting edge technology and close from the Barcelona airport (Spain). Most of the production is exported all over the world (Europe, America, Asia and Africa). <h1>STRATEGY</h1> DEVELOP AND MARKET FUNCTIONAL HEALTH INGREDIENTS FOR THE FOOD AND BEVERAGE INDUSTRY <ul> <li>By providing technological and nutritional solutions for functional food through microencapsulation</li> </ul> <ul> <li>By focusing on R&D, patents and marketing</li> </ul> <ul> <li>By providing a complete solution to our customers: food applications, clinical studies, analytical and regulatory support</li> </ul>   <h1>OUR KNOW HOW</h1> <ul><li>Fine chemistry and pharma background from the Lipotec group</li> </ul> <ul> <li>Microencapsulation and liposomes technology</li> </ul> <ul> <li>Powerful analytical capacities</li> </ul> <ul> <li>Animal and clinical studies</li> </ul> <ul> <li>Development of customer food applications</li> </ul> <ul> <li>Regulatory affairs</li> </ul>   PRODUCTS Lipophytol: water dispersible plant sterols to reduce cholesterol level in blood. Lipocal: highly bioavailable vegetarian source of calcium. Lipofer: tasteless and non prooxidative source of highly bioavailable iron. <h2>The Lipotec Group:</h2> <ul type="disc"> <li>founded in 1989 by two PhD and privately owned</li> <li>specialised in the design and production of active ingredients</li> <li>employs 200 people of which 34% have a PhD or are graduated in science</li> <li>owns 36 patents</li> <li>Investigation finds its application in three branches:</li> </ul> Cosmetic division. <ul> <li>Lipotec: development and production of actives for the cosmetic industry.</li> </ul> Pharmaceutical division. <ul> <li>BCN Peptides: synthesis and production of peptides with pharmaceutical active principles (hormons).</li> <li>GP Pharm: development and production of new hormonal and oncological drugs. </li> <li>DiverDrugs: discovery of new chemical entities for the pharma and cosmetic industries.</li> </ul> Food division. <ul> <li>Lipofoods : development and production of functional health ingredients for the food and beverage industry</li> </ul> Lipotec has its headquarters in Gavà, 15 km from Barcelona in a 16.000 m2 new facility equipped with cutting edge technology. Map [mismo vínculo que find us]   <h1>LIPOCAL: a vegetarian Source of Calcium as bioavailable as Dairy Calcium</h1> Scientific evidences indicate that dietary calcium is essential to maintain body health and to prevent major chronic diseases such as osteoporosis, arterial hypertension, obesity and colon cancer. Dietary calcium comes mainly from milk and dairy products which cover 70% of a person needs in a Western diet. However there are significant groups of people who do not eat dairy products (lactose intolerance, vegan diet, milk protein allergy, mad cow disease, taste preferences, etc.) and who do not cover their recommended calcium intake. <h3>LIPOCAL Properties</h3> - microencapsulated source of calcium - contains 36% of calcium - suitable for vegetarians - 15% more bioavailable than dairy calcium - 41% more bioavailable than tricalcium phosphate (TCP) - contains a balanced ratio Ca/P for optimal bone retention of calcium - neutral taste - improved dispersibility. <h2>Application</h2> LIPOCAL allows calcium enrichment in a wide range of foods including soy products, beverages, bakery, etc. <h2>Efficacy Tests</h2> Lipocal, TCP, dairy calcium and water (as a control) were administered to 4 groups of 5 guinea pigs. 3,43 mg of elemental calcium per kg were administered to the animals, which represent the amount of calcium that a person of 70 kg would receive after eating two yogurts of 100 g containing 120 mg of elemental calcium. Calcium blood concentration was measured every 10 minutes during 50 minutes, defining the absorption profile for every source of calcium tested. <div>  The calculation of the area under the curve (AUC) at 40 minutes for each source of calcium tested showed that LIPOCAL is 15% more bioavailable than dairy calcium and 41% more bioavailable than TCP (see values below).   Area under the curve (AUC) </div> <h1 align="left">Download Broschure <a name="OLE_LINK1" id="OLE_LINK1">LIPOFER</a>Ò: Tasteless and non Prooxidative Source of Iron</h1> Iron deficiency is the most prevalent micronutrient deficiency in the world and cause of anaemia. In Western countries there is a higher risk of iron deficiency for young children (6 months to 4 years), teenagers and women during pregnancy and menstruation period. Babies born with iron deficiency suffer a minor intellectual and psychomotor development with irreversible consequences. During infancy iron-deficiency anaemia can permanently affect brain development and in early childhood iron deficiency interferes with growth, weight gain and behavioural development. <h2>LIPOFERÒ Properties</h2> - no metallic taste - improved absorption profile - does not trigger oxidation of unsaturated fats or vitamins - does not irritate digestive tract when administered alone - is a registrated brand. Applications LIPOFERÒ DISPERSIBLE (80 mg/g of elemental iron): Powdered beverages, infant powdered milk, biscuits, bread, food supplements, hard candies, etc. LIPOFERÒ LIQUID (12 mg/ ml of elemental iron): pasteurised and UHT milk, steamed milk, yogurt (added before fermentation), fruit juices, etc. <h2>Efficacy Tests Plasma Iron concentration 2 hours after Lipofer administration.</h2> In a trial where iron absorption from Lipofer was compared to ferrous fumarate against a control, it was shown that iron concentration in blood is always higher with Lipofer with ferrous fumarate. Two hours after the administration of iron (10 mg/kg of animal weight) iron concentration in blood was 3,7 times higher with Lipofer than with ferrous fumarate (see below). In another study with rats Lipofer was shown to be 3,5 times more bioavailable than ferric pyrophosphate and 2,7 times more bioavailable than ferrous sulphate. Download Broschure LIPOPHYTOLÒ: Water dispersible Plant Sterols to lower Cholesterol High level in blood cholesterol is the first risk factor for coronary heart disease. Studies have shown that a 10% decrease in blood cholesterol level reduces cardiovascular disease risk between 19% to 54% depending on a person age. And a consumption of 1,5 g to 3 g of plant sterols (or phytosterols) per day lowers LDL Cholesterol by 8% to 15%. LipophytolÒ Properties - easy to use as a water dispersable powder - for fat-free product as it is not esterified with a fatty acid - no fat oxidation during shell-life - efficiency on lowering blood cholesterol level and atherosclerosis is demonstrated - novel food approval from the EU - registrated brand. Applications Lipophytol is a novel delivery system for phytosterols which by increasing their solubility provides a new water dispersible way of introducing phytosterols in food and beverages. The new system lowers cholesterol absorption and allows the use of sterols in 100% fat-free foods and beverages, avoiding the consumption of additional fat. Lipophytol is presented as a powder containing 70% of sterols. It can be used in dairy products, yellow fat spreads, soy drinks, food complements, etc. In each country specific legislative rules may apply for use and claims. Efficacy Tests VLDL and LDL (“bad”) cholesterol levels. In a trial with groups of 7 mice fed with 2% sterols in form of Lipophytol and 2% sterols in form of esters, bad cholesterol (LDL and VLDL) decreased dramatically in both groups compared with the control group. Atherosclerotic lesions area. After 8 weeks of being fed with a high cholesterol containing diet mice were sacrificed and atherosclerotic areas of the aorta artery quantified. The atherosclerotic area in animals fed with Lipophytol was 54% lower (statistically lower at p < 0.05) than the control group area. Publications More data about this study can be found in the following publications: Calpe-Berdiel L, Escolà-Gil JC & Blanco-Vaca F. Phytosterol-mediated inhibition of intestinal cholesterol absorption is independent of ATP-binding cassette transporter A1. British Journal of Nutrition (2006), 95, 1-6. Calpe-Berdiel L, Escolà-Gil JC, Ribas V, Navarro-Sastre A, Garcés-Garcés J & Blanco-Vaca F. Changes in intestinal and liver global gene expression in response to a phytosterol-enriched diet. Atherosclerosis (2005), 181, 75-85.